Volume 7 • 2020 • Issue 2

D entists perform more than 15 million root canals each year in the US. Despite improvements in the procedure, the failure rate for root canal interventions in the US hovers between 5% and 22%—or between 750,000 and 3.3 million a year. 1 Current root canal procedures aim to reduce bacterial load to prevent root canal failure. After infected dental pulp is removed, root canals are irrigated and then filled with synthetic materials (usually gutta percha) then capped with a crown. “Unfortunately, the possibility exists that the infecting bacteria colonies are not fully eliminated, which can leave the tooth susceptible to persistent infections,” says Dr. Anil Kishen, University of Toronto dentistry professor. Dr. Kishen has developed a nanosystem that promotes healing and regeneration of host tissues following root canals. The nanosystem includes organically-derived materials and time-released bioactive molecules to improve root canal treatment outcomes. “What we believe is that current treatment aims to eliminate bacteria. But it doesn’t influence the body to heal,” says Dr. Kishen. How does it work? Dr. Kishen’s biologically-based treatment paradigm requires an adapted root canal preparation: canals are minimally enlarged compared to the current standard. Then the bioactive nanosystem is packed into the apical portion of the root, instead of gutta percha. The nanosystem is made from chitosan, which is derived from the shells of shrimps and other crustaceans, and the shell from calcium alginate base. Both compounds are known to be safe for humans. Two molecules that promote stem cell and tissue growth, transforming growth factor beta (TGF- β ) and dexamethasone (Dex), are pre-loaded into chitosan structure. “ “TGF- β and Dex, which are time released from inside the core shell, attract host immune cells from NewMaterial May Aid Regeneration After Root Canals Although root canals relieve the pain associated with infection, the procedure results in a tooth with no living soft tissue inside.Without nerve endings or vascular supply, a tooth after a root canal is susceptible to subsequent infection. Root canal failure occurs when a previously treated tooth becomes infected, again, at the root apex. N ews and E vents 23 Issue 2 | 2020 | Be sure to check out the website at www.garrisondental.com for info on other innovative Garrison products, demo videos and our 6-month money-back guarantee. $999 Includes dentistry’s premier heavy duty stainless steel ring placement forceps, which place virtually any ring. Mention Code ADCACDA320 © 2020 Garrison Dental Solutions, LLC 150 DeWitt Lane Spring Lake, MI USA 49456 To order: Contact your authorized Garrison Dealer or Call toll free 888.437.0032 or online at www.garrisondental.com FX-KFF-10 (not shown) Contains everything listed above EXCEPT BFA-1 and TN009. $729 A system designed to handle even the toughest cases short ring tall ring wide prep ring FX400 2 pk. $299 FX500 2 pk. $299 FX600 2 pk. $299 Contoured in three dimensions, ultra-thin and dead-soft to help you recreate ideal interproximal anatomy. Full Curve Non-Stick Matrices $164 per pack FX100 4.0 mm w/ext 4.4 mm 100 pk FX150 4.1 mm w/ext 6.0 mm 60 pk FX175 5.0 mm w/ext 5.6 mm 100 pk FX200 5.4 mm w/ext 6.6 mm 100 pk FX300 6.0 mm w/ext 8.7 mm 60 pk Combining Soft-Face ™ adaptive materials, a firm inner core and advanced mechanical features to produce a wedge that truly works. Every time. Ultra Adaptive Wedges 100 ct. bulk pack $72 each FX-KFF-11 (shown) Contents: 1 – Short Ring (blue) 1 – Tall Ring (orange) 1 – Wide Prep Ring (green) 70 – Assorted Matrix Bands 80 – Assorted Ultra-Adaptive Wedges 12 – Assorted FenderWedges ® 1 – Ring Placement Forceps 1 – BFA-1 Band Placement Forceps 1 – TN009 Multi-Function Instrument